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Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease

Early evidence suggests positive effects of glutathione on human skin

This risk is not unique to semaglutide but reflects rapid metabolic improvements that can temporarily stress retinal blood vessels

These include lorcaserin, naltrexone/bupropion, phentermine/topiramate, orlistat, and the glucagon-like peptide-1 analogues liraglutide, and semaglutide