One subsequent analysis has estimated that 7.9 million individuals meet the SELECT trial criteria in the US: Among these individuals, treatment with semaglutide could prevent about 190 000 cardiovascular events in 5 years. If each eligible patient received semaglutide at a retail price of $16 188 per year, the total cost would amount to $127 billion per year. The authors of SELECT noted that: Potentially less costly alternatives for reducing obesity and CVD risk include lifestyle counseling, dietary fasting, and alternative pharmacological weight loss approaches
Chungcheongbuk-do, Republic of Korea (NCR 2019-6), and Chong Kun Dang Pharmaceutical Corp, Seoul, Republic of Korea
Brown MF, Thurmond RL, Dodd SW, Otten D, Beyer K (2002) Elastic deformation of membrane bilayers probed by deuterium NMR relaxation
Most patients experience mild gastrointestinal changes rather than severe reactions, and many find symptoms stabilize within 1 to 2 weeks as their body adapts to the medication