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It points to compounded GLP-1 medications prescribed by a licensed provider and dispensed through licensed 503A pharmacies as a cost-controlled alternative when a program denies coverage or a patient does not meet criteria

Recent Mendelian randomization findings further validate this framework: Dorea and Sellimonas appear protective, whereas Phascolarctobacterium and Ruminococcaceae UCG-004 are associated with increased PTSD risk (He et al., 2024)

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Pharmacological therapies, including antioxidants, neurotrophic agents, and metabolic modulators, can create a favorable biological environment by reducing oxidative damage, limiting neuroinflammation, stabilizing the BBB, and supporting angiogenesis