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These antibodies can neutralize the peptides intended effect, but they can also, in some cases, cross-react with endogenous peptides the body produces naturally, leading to consequences that are difficult to predict and may take months to manifest

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Overall, this chapter will provides a better understanding of the interplay between gastrointestinal tract physiology/anatomy and drug physicochemical /biopharmaceutical factors in the absorption and metabolism mechanisms that affect oral bioavailability humans

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