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Proc Natl Acad Sci USA 104:1662116626 Han J, Cheng FC, Yang Z, Dryhurst G (1999) Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinsons disease

This allows experimental solutions to remain stable during repeated use

CNS effects in cognition models remain sparse and largely confined to TBI-focused animal studies

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