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All members of the NLR family possess three conserved structural domains that determine their functional mechanisms: (1) The Nterminal effector domain (e.g., CARD, PYD, or BIR domains) mediates interactions with adaptor proteins and downstream signaling effectors, acting as the primary transducer of receptor activation signals

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For people who experience vitamin B12 deficiency, they can be a critical source of this essential vitamin the body needs to generate energy