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[47] Low vitamin concentrations in human milk occur in families with low socioeconomic status or low consumption of animal products

Overall, these SAR studies using the ternary complex structure including FBXO22, NSD2, and our next-generation NSD2 degrader, UNC10415667, revealed that UNC12149 is a more potent NSD2 degrader

In the forced swimming test, PE-22-28 reduced immobility time comparably to the SSRI fluoxetine

Due to the pharmacokinetics and tight regulation of plasma vitamin C, supplementation with vitamin C will have variable effects in vitamin C-replete (plasma concentrations near saturation) versus sub-optimal (plasma concentrations 1 g/day) vitamin C to prevent the common cold (211)