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Easier to source, cheaper than Wegovy, and Canadian clinicians prescribe it off-label routinely

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Never freeze reconstituted solution as this destroys peptide structure

Results On a patient level, Semaglutide 2.4 mg in addition to D&E compared to D&E alone, improved QALYs by 0.098 and yielded higher costs by 1,325 EUR over a 40-year time horizon, with an ICER of 13,459 EUR per QALY gained and 100% probability of cost-effectiveness at the given WTP