soul trial oral semaglutide cardiovascular outcomes 2024

soul trial oral semaglutide cardiovascular outcomes 2024 (NEJM 2025): led to a 14% ↓ in major CV events vs placebo in T2DM with ASCVD or CKD — no ↑ in serious AEs. #Semaglutide #CardioDiabetes #updatesinmedicine soul trial oral semaglutide cardiovascular

Name: soul trial oral semaglutide cardiovascular outcomes 2024 (NEJM 2025): led to a 14% ↓ in major CV events vs placebo in T2DM with ASCVD or CKD — no ↑ in serious AEs. #Semaglutide #CardioDiabetes #updatesinmedicine soul trial oral semaglutide cardiovascular
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Overall, AUCs were similar for digoxin and warfarin with ratios between AUCs close to 1.0

However, several important considerations argue for caution in extending orforglipron to pediatric populations

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