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Yes, supplementing vitamin B12 is generally very safe and beneficial especially in cases with gastrointestinal disease coupled with weight loss

However, a few side effects may be seen such as: Vomiting, nausea Loss of Appetite Diarrhea Headache Excessive urination Powered by Froala Editor Precautions & Warnings Follow these precautions and warnings before starting the medication: Talk to your doctor if you have any allergic reaction or known hypersensitivity to any medicine components

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Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on December 12th, 2025