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(158) demonstrated that colonization of germ-free (GF) mice with a cocktail of 46 Clostridium (primarily belonging to clusters IV and XIVa ) robustly increases Foxp3+ Treg numbers in the colonic lamina propria (LP) without affecting small intestinal Tregs

167 Another large study examined data on main lifetime occupation for 7,637 individuals 65 or older in the Chicago Health and Aging Project study and found that higher occupational cognitive requirements corresponded to significantly better latelife cognitive performance at baseline and to slower decline in global cognitive function over time

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