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While protein needs vary by body size, activity level, and individual goals, many adults using GLP-1 medications aim for roughly 80 to 120 grams of protein per day to help support muscle maintenance, recovery, and daily energy

As a 2022 report noted, "obesity remains the most important risk factor for the incidence and progression of osteoarthritis." According to Bliddal, the researchers launched the study to answer this question: "Would a highly effective anti-obesity medication improve KOA to a clinically meaningful degree?" Other studies had tackled the question with inconsistent results, he said

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Clinical studies have shown that this dual-action approach can be highly effective for weight management when paired with a balanced diet and regular physical activity