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One hypothesis is that we observed a greater induction of NRF2 through liver-specific Gclc deletion as compared to KEAP1 inhibition with CDDO-me because CDDO-me is a weaker inhibitor of NRF2-KEAP1 interaction compared to the ROS generated following GSH depletion
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During this study, participants were given Crystal Tomato supplements for 12 weeks
Histopathological lesion in the colon tissue of normal and acetic acid (AA) groups (H&E staining)
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