semaglutide pros cons RACGP Compounded Semaglutide: Clinical Pros, Cons

The combination of reduced caloric intake from appetite suppression, increased energy expenditure from glucagon receptor activation, and improved metabolic efficiency from GIP pathway activation creates a powerful synergy

Serious adverse events were gastroparesis, gallbladder problems, pancreatitis, and biliary diseases

Knapen MF, Mulder TP, Van Rooij IA, Peters WH, Steegers EA

A key part of this will be the SURMOUNT-Real UK study, which will look at the effects of tirzepatide in a primary care setting on weight loss, prevention of obesity-related conditions, health-related quality of life, and changes in employment status and sick day absences, compared with usual care over 5 years