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For example, melatonin has been found to stimulate the -secretase cleavage of APP in cultured neuronal and non-neuronal cells [52] via upregulation of the nonamyloidogenic ADAM10 and ADAM17 proteases

10.3389/fphys.2021.739485 44 HeW.WangP.ChenQ.LiC.et al (2020)

AMD is an important cause of blindness in the USA and accounts for 54% of blindness in Caucasian patients, 4.4% in black patients, and 14.3% in Spanish patients

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