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For people with type 2 diabetes or prediabetes, these metabolic benefits make semaglutide a dual-purpose medication that addresses multiple health concerns beyond just weight

Dehydration is one of the most common side effects reported by semaglutide and tirzepatide users, particularly in the first 48 weeks of treatment

5 Clinical trials 5.1 Chemistry of tirzepatide 5.1.1 Synthesis The chemistry of tirzepatide involves a hybrid solid-phase peptide synthesis/liquid-phase peptide synthesis (SPPS/LPPS) strategy, as described by Michael O

The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH