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These effects suggest that GLP-1R agonists may mitigate the muscular deleterious effects associated with conditions like idiopathic inflammatory myopathy (68)

By delivering comparable weight loss results to injectable semaglutide in clinical trials, without the need for injections, it provides GLP-1 therapy as an option for patients who prefer oral medications or who have avoided injectables

15,20 Serious GI AEs, though uncommon, have also been reported with GLP-1 RA therapy, including gastroparesis, intestinal obstruction, pancreatitis, and colonic ischemia

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