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Berberine has long been utilized in traditional Chinese and Ayurvedic medicine to treat conditions including inflammation, skin disorders, infections, diabetes, gastrointestinal ailments, and respiratory issues

Conversely, evening or bedtime administration may benefit some patients who find that sleeping through the initial hours after injection helps them avoid or minimize awareness of nausea

The Phase 1 study demonstrated similar pharmacokinetics, tolerability, and weight-loss responses across Asian and non-Asian participants, supporting broader global development