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While the clinical trial was extensive enough to gain FDA approval for the treatment, the longest that some patients were observed for risks and side effects was six monthsand that was only a portion of the participants from the clinical study

Analysis of antioxidant and inflammatory genes reveals GHK increases expression of 14 antioxidant genes while suppressing 2 pro-oxidant genes

doi: 10.1152/ajprenal.00174.2007 90 Carraro-LacroixLRMalnicGGirardiAC

This consequently suppresses cadmium-induced changes in apoptosis-related proteins, inhibits cadmium-induced cell apoptosis, and prevents cadmium-induced mitochondrial transmembrane potential depolarization in PC12 cells [4]