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This universality even extends to viral hepatitis, as liraglutide has been shown in vitro to directly inhibit HCV replication through an AMPK-dependent mechanism (Lee et al., 2019), reinforcing the drug classs broad impact on metabolic health critical for diverse liver pathologies

Conversely, a retrospective study with 981 patients with T2DM showed no difference in diabetic retinopathy progression between GLP-1 RAs and SGLT-2 inhibitors [94]

After 16 weeks, participants in the danuglipron groups lost significantly more body weight than those in the placebo group

Ozempics positive impact on weight loss and blood sugar management may exacerbate these cardiovascular benefits