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Phelan SM, Bauer KW, Bradley D, Bradley SM, Haller IV, Mundi MS, et al

Yes, this is essentially the aliquoting strategy described in this guide

This results in improved half-life and increased activity due to extended bioavailability in the body

In ALS, there is an abnormal cytoplasmic aggregation of misfolded proteins, mainly DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS) (Wijesekera and Leigh 2009)