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There is more work to be done to understand the mechanism of benefit as the population had a median [body mass index] of 28.6 and the relationship between the outcome and weight loss was very weak

Long-chain lipids are predominantly transported out of the intestinal absorptive cells into the lymphatic circulation [43] via a multistep process including micelle formation with bile salts, intracellular de-esterification, re-esterification, packaging into lipoproteins, and extrusion across the enterocyte basolateral membrane into the lymph [44, 45]

Advances in Experimental Medicine and Biology, 1228, 91105

The Auranofin-COJEC combination exhibited an additive effect in both LU-NB-1 and LU-NB-3R organoids (Fig