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These half-steps give each receptor system more time to adapt

These medications, originally approved by the FDA for the treatment of Type 2 diabetes, have since been authorized for weight loss therapy and are now recommended by the American Diabetes Association as potential first-line options for both indications

GLP-1 medicines are started low and stepped up deliberately: for Wegovy, 0.25 mg for weeks 1 to 4, then 0.5 mg, 1 mg, 1.7 mg, reaching the 2.4 mg maintenance dose at week 16

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