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So, maybe just for some broad framing, when you saw this announcement come out, what were some of the first things to go through your mind

doi: 10.1210/jc.2013-2117 113 GadelhaMBexMFeeldersRAHeaneyAPAuchusRJGilis-JanuszewskaAet al

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The CD4+/CD8+ ratio serves as a key marker of immune system aging, with a shift toward CD8+ dominance often linked to chronic inflammation, reduced pathogen defense, and heightened all-cause mortality risk