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417 A list of completed and ongoing trials using mTORC1 inhibitors is provided in ref

Unlike beta-1 receptors in cardiac tissue or beta-2 receptors in smooth muscle, beta-3 receptors are predominantly expressed in adipose tissue and bladder, with limited cardiovascular effects

Regular monitoring appointments are essential to assess treatment response, manage side effects, and provide ongoing lifestyle support

Activated NKT cells utilize glutamine to fuel the tricarboxylic acid cycle and GSH synthesis, with nitrogen derived from glutamine driving protein glycosylation through the hexosamine biosynthetic pathway [137]