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So it follows that continuing treatment helps preserve weight loss over time. Mir Ali, MD In the other placebo-controlled trial, SURMOUNT-MAINTAIN, the researchers investigated the efficacy and safety of maximum tolerated dose (MTD) tirzepatide and a lower 5 milligram (mg) dose for maintaining body weight reduction in adults with obesity

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Health plan officials projected annual spending on the drugs would rise from about $170 million in 2024 to more than $1 billion by 2030