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198 A randomized placebo-controlled trial in 50 patients on hemodialysis found that supplementing with a probiotic formulation containing Lactobacillus sporogenes and fructo-oligosaccharides (FOS) (ie, fermentable prebiotic fibers) for eight weeks led to increased hematocrit, hemoglobin, and red blood cell counts, as well as improved markers of iron status

Because the amount used for this condition is only small

Zinc sulfate improves insulin resistance, oxidative stress and apoptosis in liver tissues of PCOS rats through the NF-B pathway

Preclinical data consistently show neuroprotective effects, though the dedicated EVOKE trial of semaglutide for Alzheimer's disease found no significant benefit