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Reducing the dose may reduce symptoms, but it may also reduce clinical benefit

But smaller doses are not simply lighter versions of full treatment and may not help you lose the weight you want, says Zhaoping Li, MD, a professor of medicine and the chief of the division of clinical nutrition at UCLA Health in California

If you have plateaued on current medications, have fatty liver disease, or simply want to understand what is coming next, retatrutide is the most promising drug in the pipeline

Given the network effects of obesity and the added mortality impact of social isolation/loneliness among individuals with obesity, new interventions should be studied to promote social connectivity in conjunction with GLP-1 use [191,192]