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Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients

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A subset of cultured cells expressed GLP- 1 receptor, and mice with a-cell specific GLP- 1 receptor knockout have mild glucose intolerance and higher glucagon secretion in response to glucose challenges than animals of the wild type, which may indicate that GLP- 1 directly affects this cell [69]

A previous study revealed that genistein can enhance the AMPK signaling pathway and SIRT1 activity through GPER activation, subsequently inhibiting the expression of genes associated with hepatic lipogenesis and further influencing liver metabolic status [169]