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Food, particularly carbohydrates and fats, can cause the release of insulin and somatostatin, which can blunt sermorelin's ability to stimulate the pituitary gland

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Cardiovascular Effects Blood Pressure and Circulation PT-141 is known to cause temporary spikes in blood pressure, which may be problematic for women with hypertension, migraines, or cardiovascular conditions

In this context, blood glucose remains normal, pH stays within the normal range (7.387.42), bicarbonate levels are normal (2228 mEq/L), ketones usually range between 0.5 and 3 mmol/L (sometimes higher during prolonged fasting), and there is no metabolic acidosis