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This pointed to a mechanism independent of muscle l-carnitine accretion and energy production

2014;176(1):2723 Available from: Flores-Mateo G, Navas-Acien A, Pastor-Barriuso R, Guallar E

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For example, in particulate matter exposure-related models, GLS1-mediated enhancement of glutaminolysis, together with alterations in local Gln/-KG levels, can be accompanied by enhanced M1-like polarization, and inhibition of GLS1 can alleviate this pro-inflammatory polarization trend (60)