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The levels of cell cycle inhibitors P21 CIP1 and P27 Kip1 were also altered in Gstp1/2 / reinforcing the conclusion of an impaired progression in G1 phase in mutant mice (Figure 5c)

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The goal of this structured approach is to make the transition into a maintenance phase more sustainable, with dietary and physical activity habits continuing beyond the active weight-loss period

The GSTs are enzymes responsible for conjugating xenobiotics with GSH and also are commonly associated with lung diseases including COPD [41]