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The volumetric finding is a hypothesis worth testing in a powered trial with volume change as a prespecified endpoint, not a demonstration that the drug protects brain tissue
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10.1111/1753-0407.12076 160 RosalynS
It is primarily produced by the liver in response to stimulation by Human Growth Hormone (HGH) and acts as the primary mediator of HGHs muscle-building effects
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