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This medication is commonly prescribed by doctors for the following conditions: Various peripheral neuropathies that can be influenced by the three vitamins, including: polyneuropathy, neuralgia, sciatica, lumbago (lower back pain), shoulder-arm syndrome, intercostal neuralgia, trigeminal neuralgia, numbness in the extremities,

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These observations suggest that the actions of DSIP on substance P, beta-endorphin, and corticosterone are indicative of a wider array of biochemical modifications, proposing that DSIP may trigger a cascade of molecular events that may facilitate its stress-modulatory functions