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In ALS patients, no significant differences in serum IL-2 levels versus control subjects were reported [82, 83] suggesting that this cytokine might have a limited input in the immune system response, at least in the early stage of disease (14.3 9.34 months disease duration in [83])

Meanwhile, they found that macrophages in TLR2 knockout mice also phagocytosed ferroptotic cells well, suggesting that in addition to TLR2 recognition of SAPE-OOH, there were other pathways to maintain the phagocytic clearance of ferroptotic cells

These antioxidants are instrumental in neutralizing free radicals and mitigating cellular damage, thus promoting longevity

Record symptom timing: note what changed before sleep worsened