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Strikingly, the displacement of the intracellular tip of TM6 in the CCKRG protein structures (i.e., CCK1RG s and CCK2RG q ) is smaller than that observed in most other class-A GPCRG s structures, but similar to the G i/q -bound GPCRs (Supplementary Fig

As electrons pass through the complexes of the ETC some leak out to molecular oxygen (O 2 ) resulting in the formation of superoxide

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