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Factors that may influence provider recommendations include: Personal wellness goals Body composition and metabolic rate Nutrient levels or oxidative stress status Whether injections are administered intravenously or intramuscularly Findings from a licensed healthcare providers evaluation, such as labs or symptom history Licensed healthcare providers may start with lower doses, such as 600 mg weekly, and adjust based on individual response and tolerance

These findings not only reinforce the potential of topiramate as a neuroprotective agent but also provide a theoretical foundation for its application in migraine models