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However, they also have limitations: many are unstable in the gut, so they are often given by injection, and some have limited human data outside of specific indications

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Conducted in 5 countries, the study compared semaglutide 2.4 mg with placebo among 304 adults without diabetes who were obese or overweight and had at least 1 weight-related comorbidity

Direct Effects on Blood Pressure Blood pressure fluctuations appear in the list of reported effects from BPC-157 users, though this effect shows considerable individual variation