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doi: 10.1128/JB.01798-08

Now back to this, GLP-1 hormone, which is the star of the drug

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60 The Km of the human NNMT enzyme for NAM (approximately 430 M) is much higher than the affinity of NAMPT for NAM ( 0.1 mM in mammalian plasma, which can only be used by spleen, small intestine, pancreas, kidney and liver