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As adults age, natural growth hormone production declines, which can contribute to increased fat storage and slower metabolic function

NHS, NICE, and BDA resources highlight several potential risks associated with ketogenic eating: Keto flu : Headaches, fatigue, nausea, and irritability during the initial adaptation phase, related to early fluid and electrolyte shifts as glycogen stores are depleted

[1] This selectivity, first documented by Raun and colleagues in the landmark 1998 paper that called ipamorelin "the first selective growth hormone secretagogue," remains its defining characteristic in the research literature

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