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However, there are several side effects caused by NAM, limiting the application of NAM

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And a comprehensive review published in Climacteric (2022) confirmed that skin collagen levels decrease fairly rapidly in early menopause, with approximately 30% reduction in the first five years, followed by a further decline of around 2% per year for the subsequent 15 years (Kamp et al., 2022)

Eat smaller, more frequent meals instead of large ones Large meals can worsen nausea and bloating