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The contribution of nicotinamide nucleotide transhydrogenase to peroxide detoxification is dependent on the respiratory state and counterbalanced by other sources of NADPH in liver mitochondria

These NSPs are able to assemble into the replication and transcription complex (RTC) to initiate viral RNA replication and transcription

Combined triad-GSH metabolism model simulations: quinone metabolism and ROS production Following the parameterisation and sensitivity analysis, the triad model was expanded to include GS-H 2 Q adduct formation (quinone removal) and was combined with the glutathione metabolism model constructed by Reed et al

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