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Further studies revealed that Sirt5 plays an important role in supporting cancer cell metabolism by regulating various enzyme activities and protecting glutaminase C (GAC), an enzyme essential for glutamine catabolism, from degradation

The control group mice were provided with the same water after 1 h of water withdrawal

In a 2021 study in obese mice, 5-amino-1MQ administration caused significant body mass reductions in the rodents, who achieved body composition and liver adiposity parameters that were comparable to the lean mice in the control group