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The result of GLP-1r activation can differ depending on spatial and temporal factors

A composite analysis of 8 cardiovascular outcomes trials completed in 2021 demonstrated reduced incidence of major cardiovascular events by 14% and cardiovascular death by 13% (NCT01147250, NCT01179048, NCT01720446, NCT01144338, NCT02465515, NCT01394952, NCT02692716, NCT03496298)

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It is also believed that antioxidants, when co-ingested with proteins or other food nutrients, can either enhance or reduce the bioavailability of antioxidants, depending on the type of antioxidant and/or food nutrient