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body adjustment period), therapeutic dose range (where appetite suppression begins and weight loss typically starts), and maintenance dose (the long-term stable dose at which most clinical trial results are measured)

This is a meaningful difference from medications that target the vascular system

Here are some key benefits: The major issue that concave optimization faces is the presence of multiple minima and saddle points

Giuseppe Giannini, [email protected], [email protected] These authors have contributed equally to this work ORCID: Giuseppe Giannini, orcid.org/0000-0002-7127-985X