More studies using high quality MRS methods in a variety of brain regions are needed in the future to test this putative hypothesis
2.4 Combining DPI, MitoQ and vincristine induces cell death of MNA NB cells To characterize the interaction between MitoQ, DPI, and vincristine, we assessed their effects on cell death at IC50/2 and IC50/3 concentrations in four NB cell lines: Be(2)-C (MNA), IMR-32 (MNA), IMR-5/75 (MNA with MYCN downregulatable), and SH-SY5Y/MYCN (non-MNA, MYCN-inducible)
As star players in the somatotropic feedback system, this codependency is not surprising
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