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It also directly binds to KDM6A, leading to the demethylation of H3K27me3, the upregulation of Bcl-2, the suppression of Foxp3 expression, and ultimately the promotion of iTreg apoptosis [83]

In-situ hybridization-based quantification of hTR: a possible biomarker in malignant melanoma

In the public-service category, Salim Abdool Karim and Quarraisha Abdool Karim, both at the Centre for AIDS Programme of Research in South Africa, in Durban, were recognized for developing life-saving approaches to prevent and treat HIV infections