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Since the GLP-1 hormone acts directly on the stomach muscles by reducing the rate of gastric contractions, Wegovys amplified dose has caused individuals to experience a pronounced slowing of gastric emptying, which has caused severe gastroparesis side effects

31,35-37 Prospective trials are needed to further explore this potential adverse event and worsened DR, which is the central premise of the ophthalmic FOCUS trial that is expected to release results in 2026

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The conversions of O 2 into H 2 O 2 or from other biosynthetic pathways increased the total concentration of H 2 O 2 by 89.16% over control under stress (Fig