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Whilst this study primarily focused on metformin-mediated effects in tumour cells, increasing evidence implicates a role for metformin in the modulation of immune cells, with metformin demonstrated to modulate macrophage polarisation (71) and the infiltration and function of T-cells (72, 73)

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Similarly Ipamorelin has been researched for bone growth and repair

deficiency may worsen the inflammatory and demyelination processes and slow remyelination and repair processes