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Liraglutide treatment was associated with increased mean resting pulse at end-of-treatment compared with baseline (two to three beats per min)

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Elevated IGF-1 levels can persist even as the CJC-1295 concentration begins to wane

Sources The New England Journal of Medicine: Tirzepatide Once Weekly for the Treatment of Obesity Zepbound Eli Lilly: Zepbound Coverage and Savings for Patients Zepbound Eli Lilly: Zepbound Coverage and Savings for Healthcare Providers Eli Lilly Investors: Lillys tirzepatide delivered up to 22.5% weight loss in adults with obesity or overweight in SURMOUNT-1 Eli Lilly Investors: Tirzepatide demonstrated significant and superior weight loss compared to placebo in two pivotal studies FDA Label: MOUNJARO (Tirzepatide Injection) Medication Guide FDA Label: ZEPBOUND (Tirzepatide Injection) Medication Guide Important Medical Information and Disclaimers Important Current Status Update: On March 19, 2025, the FDA ended enforcement discretion for compounded tirzepatide